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Top 7 Type 2 Diabetes Medications

Some people who have type 2 diabetes can achieve their target blood sugar levels with diet and exercise alone, but many also need diabetes medications or insulin therapy. The decision about which medications are best depends on many factors, including your blood sugar level and any other health problems you have. Your doctor might even combine drugs from different classes to help you control your blood sugar in several different ways.

1. Metformin
Generally, metformin is the first medication prescribed for type 2 diabetes. It works by improving the sensitivity of your body tissues to insulin so that your body uses insulin more effectively. Metformin also lowers glucose production in the liver. Metformin may not lower blood sugar enough on its own. Your doctor will also recommend lifestyle changes, such as losing weight and becoming more active.

2. Meglitinides
These medications work like sulfonylureas by stimulating the pancreas to secrete more insulin, but they’re faster acting, and the duration of their effect in the body is shorter. They also have a risk of causing low blood sugar, but this risk is lower than with sulfonylureas. Weight gain is a possibility with this class of medications as well. Examples include repaglinide (Prandin) and nateglinide (Starlix).

3. Thiazolidinediones
Like metformin, these medications make the body’s tissues more sensitive to insulin. This class of medications has been linked to weight gain and other more-serious side effects, such as an increased risk of heart failure and fractures. Because of these risks, these medications generally aren’t a first-choice treatment. Rosiglitazone (Avandia) and pioglitazone (Actos) are examples of thiazolidinediones.

4. Sulfonylureas
These medications help your body secrete more insulin. Examples of medications in this class include glyburide (DiaBeta, Glynase), glipizide (Glucotrol) and glimepiride (Amaryl). Possible side effects include low blood sugar and weight gain.

5. GLP-1 receptor agonists
These medications slow digestion and help lower blood sugar levels, though not as much as sulfonylureas. Their use is often associated with some weight loss. This class of medications isn’t recommended for use by itself. Exenatide (Byetta) and liraglutide (Victoza) are examples of GLP-1 receptor agonists. Possible side effects include nausea and an increased risk of pancreatitis.

6. SGLT2 inhibitors
These are the newest diabetes drugs on the market. They work by preventing the kidneys from reabsorbing sugar into the blood. Instead, the sugar is excreted in the urine. Examples include canagliflozin (Invokana) and dapagliflozin (Farxiga). Side effects may include yeast infections and urinary tract infections, increased urination and hypotension.

7. DPP-4 inhibitors
These medications help reduce blood sugar levels, but tend to have a modest effect. They don’t cause weight gain. Examples of these medications are sitagliptin (Januvia), saxagliptin (Onglyza) and linagliptin (Tradjenta).


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  1. Exploring “amazing fivu com” (Google it) will assist you to recover from diabetic issues and achieve a healthy way of life. For a time frame of 1 ½ months, my husband has been a keen follower of the plan. It`s been five years since he has been taking insulin shots. He has been a type 2 diabetes patient for 6 years. His eating routine have favorably altered since he has been a keen reader and follower of this program..

  2. SGL2 inhibitors also have a higher risk of amputations among other things. Google them along with lawsuits.

  3. fuck…n idiots.., best medicaments for diabetes typ 2 is good raw food and diet, not pharma shit…

  4. bahut hee bore video hai , kripya muh se bol kar kuchh vyakhya kare

  5. Music= Sarah Smile ripoff. DONT TAKE DRUGS TAKE CEYLON CINNAMON and Exercise.
    Look on Youtube for videos by===>>>
    Dr Jason Fung.

  6. Sir, you are too fast in erasing your comments. What is the hurry..I had to stop yr video midway..

  7. stitch ka liye which medicine best?

  8. My doctor prescribed type 2 diabetes for me : morning – metformin 500mg, voglibose 0.2mg, januvia sitagliptin 100mg, glimperide 2mg . Afternoon – metformin 500mg. Then, night – metformin 500mg, glimperide 2mg, multi vitamin tablet. I'm taking all these daily . I don't know whether all these good or not .

  9. The only way of managing Type 2 diabetes is through diet. The only carbs you can have must come from very low glycemic index green vegetables, broccoli, kale, spinach, cabbage etc.
    Go on a predominantly plant based keto diet with fish and eggs.
    I no longer use any of the ghastly shite you have outlined in this video. Not Metformin, Januvia, Sitagliptin, Gliclazide, Apidra or Lantus.
    Carbohydrate is to us diabetics what nuts are to someone with a nut allergy.

  10. Januvia is on a "Do Not Use for 7 years" flag by a bunch of doctors.  They are fighting FDA because they approve medicines not with not enough study of them.  We passed Januvia quickly.  Europe studied it for the normal 7 years.  They discovered that too many people were developing pancreatitis after starting to take Januvia.  I took 2 pills of Januvia and dumped it after I found this info.  Besides, after the third pill it is usually shots.  I decided to control my diabetes on my own.

  11. Diabetes can be cured by natural means. Allopathic medications are a fraud!!! Please believe me. My father who was diagnosed with diabetes some 7 years back has stopped taking all allopathic medicines after about 2 years. He is now taking all herbal remedies… Allopathic doctor (read diabetologist) recommended him against taking fruits on the ground that it would increase his sugar level…After doing a detailed analysis of the advice, I found that it was basically because fructose (found in fruits) reduces glucose level in blood, and consuming more fruits would have meant that my father would not require medicines that the doctor prescribed. Today, his glucose level fluctuates between 160 and 200 and he is completely medication free… Remember,glucose level of 200 is normal, not high, as the doctors would like us to believe… In the year 1977 – 78,this was the normal range… after 20 years this level was brought down to serve vested interests…. Medical World is a fraud….Hippocrates Oath, the doctors take is baseless, devoid of intent.

  12. All waste stuff. Finally apart from diabetes you will have renal and hepatic failure.

  13. Dr.Gopalakrisnan…you are absolutely right about the drug known as Sugar.If parents conditioned their children right from childhood, and make aware of sugar intake things would improve in our society.It is sad state of affairs when we see young ones taking insulin shot or tablets before meals… people are unaware about their eating habits innocently.Education and awareness is a big need of the hour..!!

  14. Why medications so many side effects all doctors should cultivate organic crops all are healthy no diseases no medicines no patients no doctors all are healthy

  15. Metformin is not controlled sugar why??

  16. Metformin gives you the shits then kills you

  17. Diabetes Zone your way of showing vedio is not proper.you are running so fast that one can not read properly.you write & immediately delats.So it should be slower.

  18. Metformin is an old drug but it's back to being popular. Theres some promising research about its role in cancer prevention and therapy!

  19. क्या सच में किसी उपरोक्त या अन्य आयुर्वेदिक दवा से डाइबिटीज जड़ से समाप्त किया जा सकता है?? बहुत सी कम्पनियों की दवा ये कह कर कि इसे खाने से जड़ से डाइबिटीज समाप्त हो जायेगा, सीर्फ अधिक बिकने के लिए प्रचार किया जाता है….

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